Stendra Vs. Viagra

Stendra (Avanafil) is the newest prescription drug option for men with erectile dysfunction. It is now available in the United States, following FDA approval in April 2012.  Stendra is also available in may other parts of the world.

The obvious questions people have about Stendra are, “What makes Stendra better”, “How is Stendra different?” and “Is Stendra better than Viagra?”  How is Stendra Compared to Viagra?

How Is Stendra Different?

Stendra has a different chemical formulation from other erectile dysfunction medications and may work better in some men. Each ED medication works in a subtly different way, but they have a similar mechanism of action. Both Stendra and Viagra attempt to find and inhibit the phosphodiesterase-PDE5 enzyme found in the blood. The result of blocking its cGMP degradation action is to lower the blood pressure of the body and to improve blood flow. This affects areas like the pulmonary artery, but also chiefly the corpus cavernosum tissue of the blood.

Stendra acts in the same basic way as the other ED medications in that it is classed as a PDE 5 inhibitor. However, the active ingredient, Avanafil, is formulated differently from the active ingredients in the other drugs. Viagra’s active ingredient is Sildenafil, and it works by inhibiting a substance known as PDE 5. When PDE 5 is blocked or inhibited, it cannot break down another substance known as cGMP, and cGMP is necessary for increased blood flow to the sexual organs. Less PDE 5 means more cGMP, which means more blood flow to the penis; hence, an erection is easier to achieve.

When a man takes the smallest dose of Viagra (25 mg), he is 1.7 times more likely to have an erection than if he took a placebo. At the 50 mg and 100 mg dosages, he is 2.1 times more likely to have an erection. Overall, 75% of men taking Viagra reported better erections.

With Stendra, 80% of men reported improved erections. When it comes to actual sex, the rate of successful intercourse ranged from 46% to 74% for those who took the recommended starting dosage of 100 mg of Stendra. Additionally, although both Viagra and Stendra are supposed to be taken 30 minutes prior to sex, with Stendra, 66% to 72% of men reported being able to have intercourse within 15 minutes of taking it.

Researchers believe that Stendra’s action as a PDE 5 inhibitor is more specific than the action of Viagra’s PDE 5 inhibitor. If this is indeed the case, it would be roughly analogous to using a small hammer to drive a small nail into a wall rather than using a sledgehammer. While a sledgehammer will do the job, it may have other effects (like making holes in the drywall). If Stendra is a more targeted PDE 5 inhibitor than Viagra, it could mean that side effects are less severe or bothersome with Stendra. The product is still too new to be able to draw any definitive conclusions, however.

Is Stendra Better than Viagra?

Furthermore, Stendra appears to have a longer-lasting effect, when compared to Viagra. Viagra is considered ineffective after four hours, but 59% to 83% of men taking Stendra were able to function sexually a full six hours after taking it.

Are Side Effects of Stendra Similar to Side Effects of Viagra?

Stendra has a similar side effect profile to Viagra. Serious side effects, like vision problems, should be reported to a physician right away.

In general, side effects are reported at about the same rates for both Viagra and Stendra. However, the side effect of seeing a faint blue tint over everything after taking Stendra has not been reported, yet 3% of Viagra users reported this side effect. The rare side effect of hearing difficulty after taking Viagra has not been reported by Stendra users, but that may be because Stendra has not been on the market long enough for some of the rarer side effects to show up.

While Stendra is not recommended for men who take nitrates for cardiac conditions, some data indicates that Stendra is less likely to lead to a sharp drop in blood pressure for men who also take nitroglycerine. However, it is very important that men who want to take Stendra tell their physician if they take drugs for cardiac conditions.

Which Should You Choose?

There is no simple answer to whether you should take Stendra or Viagra to treat ED. Lifestyles and physiology are varied enough that what works best for one man may not work so well for another. With any of the major ED drugs, there can be a certain amount of trial and error involved with finding the best treatment. Some physicians will provide patients with sample drugs to try, because ED drugs can be expensive. In general, if you can take one ED drug safely, you can take the others safely.

You may have to try more than one ED medication to find a satisfactory treatment.

Performance anxiety can affect blood flow to the penis. Confidence is an important thing, as is desire. Stendra may give confidence to the user, but is chiefly designed for men where arousal and confidence are not problems, but something physical is. For good results, combine it with the best food to help have longer sex and good exercise. There are many types of food that improves sex, but do not combine it with grapefruits and alcohol, which will not only make Viagra less effective, but will concentrate its effects in the blood leading to a greater risk of side effects such as headaches, back pain, dyspepsia, photosensitivity and so on.  When all the data is taken into account, the answer to the question of which drug to take often comes down to personal experience. All the PDE 5 inhibitors are available by prescription only, and some physicians may prefer prescribing one of them over the others. ED is a very individualized condition, with a variety of causes and contributing factors. If you have ED, treatment should start with a consultation with a physician to ensure that PDE 5 inhibitors are safe for you to take. If so, you may have to try more than one to determine which is best for you.

Stendra Viagra
Onset of action 15-30 minutes 30-60 minutes
Plasma half-life 3 hours 4 hours
Duration of action Up to 6 hours Up to 12 hours
Effect of food intake Not affected High-fat meals decrease efficacy
Unique side effects Vision abnormalities (PDE6)

Stendra (Avanafil) is a direct competitor to Viagra, Levitra, Staxyn, and Cialis. These four drugs have been on the market for a decade or longer, though Staxyn, a dissolvable form of Levitra that does not have to be taken with water, has only been available since 2011.

Generic Stendra

Stendra is expected to be a hugely popular drug, just like the other. You can already find questionable fly-by-night internet sites offering to sell “generic” Stendra.  Note, Stendra is not available yet as a generic.  Any drug being offered as a “generic” is counterfeit and probably fake. and you should not buy from any site offering to ship a “generic” of any ED medication to the United States. Importing prescription drugs from abroad is illegal except in very specific cases, and you risk losing money, being questioned by Customs, and more importantly, ingesting something harmful that could possibly kill you.

Leave a Reply

Your email address will not be published. Required fields are marked *


*

You may use these HTML tags and attributes: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <strike> <strong>